Citation: YAN Xiao, LI Tian-xian*, FAN Zhao-jun, KOU Zheng, CHEN Sheng-liang. Sequencing and Phelogenetic Analysis of Hypervariable Region of Infectious Bursal Disease Virus vp2 Gene .VIROLOGICA SINICA, 2004, 19(6) : 620-623.

Sequencing and Phelogenetic Analysis of Hypervariable Region of Infectious Bursal Disease Virus vp2 Gene

  • Available online: 20 December 2004
  • Hypervariable region of vp2 gene of six different IBDV (Infectious bursal disease virus) isolates, which were isolated from Jiangsu province, was amplified by RT-PCR and sequenced. Furthermore, sequences of six IBDV isolates were analyzed by ClustalX and Phylip3.5. It was suggested that three isolates (Y3, P2G, P8G) were closely related to vvIBDV (very virulent IBDV) strains isolated from China and Europe. Other isolates (SZ, Y5, W04) were very close with Japanese vvIBDV strains. This study laid on foundation for the research of molecular epidemiology and the development of IBDV vaccines.

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    Sequencing and Phelogenetic Analysis of Hypervariable Region of Infectious Bursal Disease Virus vp2 Gene

    • 1. Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan 430071, China

    Abstract: Hypervariable region of vp2 gene of six different IBDV (Infectious bursal disease virus) isolates, which were isolated from Jiangsu province, was amplified by RT-PCR and sequenced. Furthermore, sequences of six IBDV isolates were analyzed by ClustalX and Phylip3.5. It was suggested that three isolates (Y3, P2G, P8G) were closely related to vvIBDV (very virulent IBDV) strains isolated from China and Europe. Other isolates (SZ, Y5, W04) were very close with Japanese vvIBDV strains. This study laid on foundation for the research of molecular epidemiology and the development of IBDV vaccines.

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