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Volume 27 Issue 4
August 2012
    Citation: Jianjun Chen. Are the H5N1 Viruses Prepared for Inter-human Transmission?* .VIROLOGICA SINICA, 2012, 27(4) : 219-220.  http://dx.doi.org/10.1007/s12250-012-3267-4
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    Are the H5N1 Viruses Prepared for Inter-human Transmission?*

    • State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan 430071, Hubei, China

    • Corresponding author: Jianjun Chen, chenjj126@126.com
    • Received Date: 03 July 2012
      Accepted Date: 12 July 2012
      Available online: 01 August 2012

      Fund Project: Foundation for Study Encouragement to Young Scientists, Chinese Academy of Sciences KSCX2-EW-J-19National Natural Science Foundation of China 310000088the National Basic Research Program of China 2010CB530301

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      1. Govorkova E A, Rehg J E, Krauss S, et al. 2005. Lethality to ferrets of h5n1 influenza viruses isolated from humans and poultry in 2004. J Virol, 79(4): 2191-2198.

      2. Han Y, Hou G, Jiang W, et al. 2012. A survey of avian influenza in tree sparrows in china in 2011. PLoS One, 7(4): e33092.
          doi: 10.1371/journal.pone.0033092

      3. Hatta M, Gao P, Halfmann P, et al. 2001. Molecular basis for high virulence of hong kong h5n1 influenza a viruses. Science, 293(5536): 1840-1842.
          doi: 10.1126/science.1062882

      4. Imai M, Watanabe T, Hatta M, et al. 2012. Experimental adaptation of an influenza h5 ha confers respiratory droplet transmission to a reassortant h5 ha/h1n1 virus in ferrets. Nature, 486(7403): 420-428.

      5. Jiang W M, Liu S, Chen J, et al. 2010. Molecular epidemiological surveys of h5 subtype highly pathogenic avian influenza viruses in poultry in china during 2007-2009. J Gen Virol, 91(Pt 10): 2491-2496.

      6. Wagner R, Matrosovich M, Klenk H D. 2002. Functional balance between haemagglutinin and neuraminidase in influenza virus infections. Rev Med Virol, 12(3): 159-166.
          doi: 10.1002/(ISSN)1099-1654

      7. Wang H, Feng Z, Shu Y, et al. 2008. Probable limited person-to-person transmission of highly pathogenic avian influenza a (h5n1) virus in china. Lancet, 371(9622): 1427-1434.
          doi: 10.1016/S0140-6736(08)60493-6

      8. Yang Y, Halloran M E, Sugimoto J D, et al. 2007. Detecting human-to-human transmission of avian influenza a (h5n1). Emerg Infect Dis, 13(9): 1348-1353.
          doi: 10.3201/eid1309.070111

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      Are the H5N1 Viruses Prepared for Inter-human Transmission?*

        Corresponding author: Jianjun Chen, chenjj126@126.com
      • State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan 430071, Hubei, China
      • Received Date: 03 July 2012
      • Accepted Date: 12 July 2012
      Fund Project:  Foundation for Study Encouragement to Young Scientists, Chinese Academy of Sciences KSCX2-EW-J-19National Natural Science Foundation of China 310000088the National Basic Research Program of China 2010CB530301

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