Citation: Raimonds Rescenko, Raitis Peculis, Monta Briviba, Laura Ansone, Anna Terentjeva, Helena Daiga Litvina, Liga Birzniece, Kaspars Megnis, Oksana Kolesova, Baiba Rozentale, Ludmila Viksna, Vita Rovite, Janis Klovins. Replication of LZTFL1 Gene Region as a Susceptibility Locus for COVID-19 in Latvian Population .VIROLOGICA SINICA, 2021, 36(5) : 1241-1244.  http://dx.doi.org/10.1007/s12250-021-00448-x

Replication of LZTFL1 Gene Region as a Susceptibility Locus for COVID-19 in Latvian Population

  • Corresponding author: Janis Klovins, klovins@biomed.lu.lv, ORCID: 0000-0001-8362-5505
  • Received Date: 30 March 2021
    Accepted Date: 24 August 2021
    Published Date: 20 October 2021
    Available online: 01 October 2021

  • 加载中
    1. Chang CC, Chow CC, Tellier LC, Vattikuti S, Purcell SM, Lee JJ (2015) Second-generation PLINK: rising to the challenge of larger and richer datasets. GigaScience 4: 7
        doi: 10.1186/s13742-015-0047-8

    2. COVID-19 Host Genetics Initiative (2021) Mapping the human genetic architecture of COVID-19. Nature. https://doi.org/10.1038/s41586-021-03767-x.
        doi: 10.1038/s41586-021-03767-x

    3. Genome Wide Association Study (GWAS) catalog (2021). Available: https://www.ebi.ac.uk/gwas/efotraits/MONDO_0100096. Accessed 26 March 2021

    4. GTEx Consortium (2017) Genetic effects on gene expression across human tissues. Nature 550: 204-213
        doi: 10.1038/nature24277

    5. Hu J, Li C, Wang S, Li T, Zhang H (2021) Genetic variants are identified to increase risk of COVID-19 related mortality from UK Biobank data. Hum Genomics 15: 10
        doi: 10.1186/s40246-021-00306-7

    6. Liu D, Yank J, Feng B, Lu W, Zhao C, Li L (2020) Mendelian randomization analysis identified genes pleiotropically associated with the risk and prognosis of COVID-19. J Infect 82: 126-132

    7. Maya EAL, van der Graaf A, Lanting P, van der Geest M, Fu J, Swertz M, Franke L, Wijmenga C, Deelen P, Zhernakova A, Sanna S, Lifelines Chort Study (2020) Lack of association between genetic variants at ACE2 and TMPRSS2 genes involved in SARS-CoV-2 infection and human quantitative phenotypes. Front Genet 11: 613
        doi: 10.3389/fgene.2020.00613

    8. Pairo-Castineira E, Clohisey S, Klaric L, Bretherick A, Rawlik K, Pasko D, Walker S, Wilson J, Baillie K (2021) Genetic mechanisms of critical illness in COVID-19. Nature 591: 92-98
        doi: 10.1038/s41586-020-03065-y

    9. Park JH, Jang W, Kim SW, Lee J, Lim YS, Cho CG, Park SW, Kim BH (2020) The clinical manifestations and chest computed tomography findings of coronavirus disease 2019 (COVID-19) patients in China: a proportion meta-analysis. Clin Exp Otorhinolaryngol 13: 95-105
        doi: 10.21053/ceo.2020.00570

    10. Promchan K, Natarajan V (2020) Leucine zipper transcription factor-like 1 binds adaptor protein complex-1 and 2 and participates in trafficking of transferrin receptor 1. PLoS One 15: e0226298
        doi: 10.1371/journal.pone.0226298

    11. Rovite V, Wolff-Sagi Y, Zaharenko L, Nikitina-Zake L, Grens E, Klovins J (2018) Genome database of the Latvian population (LGDB): design, goals, and primary results. J Epidemiol 5: 353-360

    12. Shelton JF, Shastri AJ, Te C, Ye C, Weldon CH, Filshtein-Somnez T, Coker D, Symons A, Esparza-Gordillo J, 23andMe COVID-19 Team, Aslibekyan S, Auton A (2021) Trans-ancestry analysis reveals genetic and nongenetic associations with COVID-19 susceptibility and severity. Nat Genet 53: 801-808
        doi: 10.1038/s41588-021-00854-7

    13. The 1000 Genomes Project Consortium, Auton A, Brooks LD, Durbin RM, Garrison EP, Kang HM, Korbel JO, Marchini JL, McCarthy S, McVean GA, Abecasis GR (2015) A global reference for human genetic variation. Nature 526: 68-74
        doi: 10.1038/nature15393

    14. The Severe COVID-19 GWAS Group (2020) Genomewide association study of severe Covid-19 with respiratory failure. N Engl J Med 383: 1522-1534
        doi: 10.1056/NEJMoa2020283

    15. Zeberg H, Pääbo S (2020) The major genetic risk factor for severe COVID-19 is inherited from Neanderthals. Nature 587: 610-612
        doi: 10.1038/s41586-020-2818-3

    16. Zhou W, Zhao Z, Nielsen JB, Fritsche LG, LeFaive J, Taliun SAG, Bi W, Gabrielsen ME, Daly MJ, Neale BM, Hveem K, Abecasis GR, Willer CJ, Lee S (2020) Scalable generalized linear mixed model for region-based association tests in large biobanks and cohorts. Nature 52: 634-639

  • 加载中

Figures(1) / Tables(1)

Article Metrics

Article views(3065) PDF downloads(3) Cited by()

Related
Proportional views

    Replication of LZTFL1 Gene Region as a Susceptibility Locus for COVID-19 in Latvian Population

      Corresponding author: Janis Klovins, klovins@biomed.lu.lv
    • 1. Latvian Biomedical Research and Study Centre, Riga 1067, Latvia
    • 2. Riga Stradins University, Riga 1007, Latvia

    Abstract: