First insight into the virome composition of the vulnerable <em>Naemorhedus griseus</em>

Yu Guo; Meijing Hong; Xuefei Sun; Yuhang Liu; Yue Sun; Le Yi; Biao He; Changchun Tu; Guoqiang Zhu; Zhongzhong Tu

doi:10.1016/j.virs.2026.08.009

October 2026

Citation: Yu Guo, Meijing Hong, Xuefei Sun, Yuhang Liu, Yue Sun, Le Yi, Biao He, Changchun Tu, Guoqiang Zhu, Zhongzhong Tu. First insight into the virome composition of the vulnerable Naemorhedus griseus .VIROLOGICA SINICA, 2026, 41(5) : 1033-1044. http://dx.doi.org/10.1016/j.virs.2026.08.009

First insight into the virome composition of the vulnerable Naemorhedus griseus

Yu Guo ^a,b ,
Meijing Hong ^c ,
Xuefei Sun ^b,d ,
Yuhang Liu ^b ,
Yue Sun ^b ,
Le Yi ^b ,
Biao He ^b ,
Changchun Tu ^a,b ,
Guoqiang Zhu ^{a
,,} ,
Zhongzhong Tu ^{b
,,}

a. Jiangsu Co-Innovation Center for the Prevention and Control of Important Animal Infectious Disease and Zoonoses, Yangzhou University, Yangzhou 225009, China;
b. Key Laboratory of Jilin Province for Zoonoses Prevention and Control, State Key Laboratory of Pathogen and Biosecurity, Academy of Military Medical Sciences, Changchun 130122, China;
c. Chifeng Saihanwula National Nature Reserve Administration, Daban 025150, China;
d. College of Veterinary Medicine, Jilin University, Changchun 130062, China

Corresponding author: Guoqiang Zhu, yzgqzhu@yzu.edu.cn
Zhongzhong Tu, tudong890901@163.com
Received Date: 09 January 2026
Accepted Date: 10 August 2026
Available online: 11 August 2026

Abstract

The Chinese goral (Naemorhedus griseus) is identified as a vulnerable species on the Red List of China's Biodiversity and listed as a national second-class key protected wild animal in China. Despite its widespread distribution in China, there has been scant research into the pathogens harbored by this species, and our understanding of the virus diversity remains limited. In the present study, we performed the whole virome profiling of a rescue-failed Naemorhedus griseus, which identified a diverse viral community across multiple organ tissues of the animal. Specifically, abundant bacteriophages, several plant-derived viruses, and multiple mammalian viruses, i.e., two distinct parvoviruses, novel picobirnaviruses, and a novel phenuivirus. Additionally, virus-carrier determination analysis that Naemorhedus griseus-borne viruses are related to plants, mammals, and arthropods. These data provide the first insight into the genetic diversity of Naemorhedus griseus-borne viruses, and their transmission dynamics across humans, domestic animals, arthropods, and wildlife. This study not only expands the existing repertoire of viral genomic information and delineates the host range of these pathogens but also underscores the imperative of implementing a One Health strategy for the surveillance and control of wildlife-borne viral pathogens.
- Naemorhedus griseus
- , Virome
- , Parvovirus
- , Picobirnavirus
- , Phenuivirus

Electronic Supplementary Material

10.1016j.virs.2026.08.009-ESM.docx
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