EFFECT OF RIBAVIRIN ON THE SPCEIFIC HUMOUR AL IMMUNITY RESPONSES OF EHF PATIENTS
Abstract: Using a micro-ELISA technique, the serum specific IgG and IgM antibody of the EHF patients were measured sequencially as a part of a doubleblind, placebo-controlled clinical trial of ribavirin therapeutic efficacy in the treatment of EHF. The results showed a significant decrease of antibody levels in the ribavirin-treated group (p<0.001 in IgG, p<0.05 in IgM). It suggests that ribavirin has an inhibition effect on the EHF patients antibody responses. Therefore it may reduce the formation of the circ...