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Citation: SHEN Hong-Kai, YAO Gai-Xin. Study of Cytopathic Effects and Reproduction of Epidemic Hemorrhagic Fever Virus(EHFV) in Human Lymphocyte Cell Line [J].VIROLOGICA SINICA, 1988, 3(2) : 173.

Study of Cytopathic Effects and Reproduction of Epidemic Hemorrhagic Fever Virus(EHFV) in Human Lymphocyte Cell Line

  • A human lymphocyte cell line was inoculated with Chen, L99, and SR11 strains of EHF virus respectively. Cytopathic effects(CPE) were observed for 5—7 days after inoculation. First of all, the cells granulated and rounded up, then cell degeneration occured rapidly. The clustered and clumed cells still adhered cn the glass surface without forming syncytium. Some 48—72 hours after the CPE appeared, the cells fell off completely from the glass surface. Specific immunoflorescent particles were examined in the cy...

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    Study of Cytopathic Effects and Reproduction of Epidemic Hemorrhagic Fever Virus(EHFV) in Human Lymphocyte Cell Line

    • 1. Department of Virology
    • 2. Anhui Institute of Medical Sciences

    Abstract: A human lymphocyte cell line was inoculated with Chen, L99, and SR11 strains of EHF virus respectively. Cytopathic effects(CPE) were observed for 5—7 days after inoculation. First of all, the cells granulated and rounded up, then cell degeneration occured rapidly. The clustered and clumed cells still adhered cn the glass surface without forming syncytium. Some 48—72 hours after the CPE appeared, the cells fell off completely from the glass surface. Specific immunoflorescent particles were examined in the cy...

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