Susceptibilty and Pathogenesis Study of Tupaia Belanger Yunalis to Experimental Infection with Russian Spring-Summer Encephalitis Virus
Abstract: Chinese tupaia belangeri yunalises were infected with Russian spring summer encephalitis viruses (Dongbai, YH, T57 strains) by intracerebral, intraperitoneal and subcataneous route. All tupaia belangeri yunalies had viremia and lasted for 7—9 days. Immune response depended on pathogen which light pathological change induced good immune response HI antibody, neutralizing antibody and CF antibody were checked out on 5th, 7th and 13thday, respectively. The growth of both HI antibody and neutralizing antibody w...