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Volume 08 Issue 3
June 1993
    Citation: GAO You-Xin, LIU Jian-Jun, YANG Tie-Qiu, TAO Hua-Jun, CENG Qiang-Bin, BANG Qian. An Experimental Animal Model Study on Infection and Pathogensis of HCMV-AD_(169) Strain .VIROLOGICA SINICA, 1993, 8(3) : 290-292.
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    An Experimental Animal Model Study on Infection and Pathogensis of HCMV-AD_(169) Strain

    • 1.

      Institute of Virology Hubei Medical College

    • 2.

      Wuhan

    • 3.

      0071

    • 4.

      0071

    • Available online: 05 September 1993
    • This paper is a study on the result of animal model with HCMV. Rabbits were inoculated with HCMV-AD_(169) strain. The duration of viremic stage of rabbits infected with HCMV was studied by means of immunoflourescent assays and reisolation of the virus. Specific flourescence for HCMV anti- gen was first observed in both monocytes and lymphocytes in the blood on 13th day,and released the virus to the plasma. It was indicated that HCMV was disseminated to rabbits body, thus caused target or- gans infection.
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      An Experimental Animal Model Study on Infection and Pathogensis of HCMV-AD_(169) Strain

      • 1. Institute of Virology Hubei Medical College
      • 2. Wuhan
      • 3. 0071
      • 4. 0071

      Abstract: This paper is a study on the result of animal model with HCMV. Rabbits were inoculated with HCMV-AD_(169) strain. The duration of viremic stage of rabbits infected with HCMV was studied by means of immunoflourescent assays and reisolation of the virus. Specific flourescence for HCMV anti- gen was first observed in both monocytes and lymphocytes in the blood on 13th day,and released the virus to the plasma. It was indicated that HCMV was disseminated to rabbits body, thus caused target or- gans infection.

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