THE STUDY OF DETERMINATION OF HBCAG IN PERIPHRAI BLOOD WITH RIA AND ELISA

HUANG Hua-Fang; JIN Wei-E; YAO Meng-Ling; XIONG Kai-Jun; WANG Xin-He; DAI Jia-Zhu; FAN Hong-Mei; ZENG Lian-Lan

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April 1986

HUANG Hua-Fang, JIN Wei-E, YAO Meng-Ling, XIONG Kai-Jun, WANG Xin-He, DAI Jia-Zhu, FAN Hong-Mei and ZENG Lian-Lan. THE STUDY OF DETERMINATION OF HBCAG IN PERIPHRAI BLOOD WITH RIA AND ELISA[J]. Virologica Sinica, 1986, 1(2).

Citation: HUANG Hua-Fang, JIN Wei-E, YAO Meng-Ling, XIONG Kai-Jun, WANG Xin-He, DAI Jia-Zhu, FAN Hong-Mei, ZENG Lian-Lan. THE STUDY OF DETERMINATION OF HBCAG IN PERIPHRAI BLOOD WITH RIA AND ELISA .VIROLOGICA SINICA, 1986, 1(2) : 13.

RIA法及ELISA法检测血清中HBcAg

1.
同济医科大学附属协和医院传染病学教研组
2.
同济医科大学附属协和医院传染病学教研组武汉

摘要

HBcAg 是 Dane 颗粒的核心部分的组成成分,为乙肝病毒复制的重要指标。我科先后应用 RIA 及 ELISA 法检测 HBcAg 阳性的乙型肝炎患者94例,其中28例血清 HBcAg 阳性,检出率为29.8%,同时以 HBeAg、DNAP、抗-HB_c 等感染指标进行比较,显示出一定的敏感性及特异性,并可应用于临床作为估计传染性、预后及抗病毒药物疗效观察的较好指标,特别是 ELISA 法不要特殊的仪器设备更适于推广应用。

THE STUDY OF DETERMINATION OF HBCAG IN PERIPHRAI BLOOD WITH RIA AND ELISA

1.
Department of infectious disease
2.
Xianhu Hospital

Abstract

HBcAg is the constructional protein antigen of core component of HBV.It s presence in peripheral blood has been used as an important mar? ker of replication of HBV.We had studied the detection of HBcAg in 94 HBsAg positive cases of viral hepatitis with the methods of RIA and ELISA,and compared with the survey of HBeAg,anti-HBc and HBV- DNAp.HBcAg was found to be positive in sera of 28 cases(29.8%).The results suggested that the determination of HBcAg with the method of ELISA and RIA is comparatively sensiti...

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通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142

THE STUDY OF DETERMINATION OF HBCAG IN PERIPHRAI BLOOD WITH RIA AND ELISA

1. Department of infectious disease
2. Xianhu Hospital

Abstract: HBcAg is the constructional protein antigen of core component of HBV.It s presence in peripheral blood has been used as an important mar? ker of replication of HBV.We had studied the detection of HBcAg in 94 HBsAg positive cases of viral hepatitis with the methods of RIA and ELISA,and compared with the survey of HBeAg,anti-HBc and HBV- DNAp.HBcAg was found to be positive in sera of 28 cases(29.8%).The results suggested that the determination of HBcAg with the method of ELISA and RIA is comparatively sensiti...