Studies on apoptosis of HeLa cell induced by vaccinia virus

ZHANG Xiao-qing; LIU Yu; DING Ming-Xiao

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August 1998

ZHANG Xiao-qing, LIU Yu and DING Ming-Xiao. Studies on apoptosis of HeLa cell induced by vaccinia virus[J]. Virologica Sinica, 1998, 13(4).

Citation: ZHANG Xiao-qing, LIU Yu, DING Ming-Xiao. Studies on apoptosis of HeLa cell induced by vaccinia virus .VIROLOGICA SINICA, 1998, 13(4) : 368.

痘苗病毒诱导HeLa细胞的凋亡

1.
北京大学生命科学学院

摘要

痘苗病毒感染ＨｅＬａ细胞后形态学上出现了较典型的细胞凋亡特征，电泳分析显示出ＤＮＡ阶梯，用ＤＮＡ断裂原位检测技术发现其染色质断裂主要存在于核周，与染色质凝聚位置相似。
- 细胞凋亡痘苗病毒 HeLa细胞

Studies on apoptosis of HeLa cell induced by vaccinia virus

1.
College of Life Sciences,Peking University

Abstract

After infecting with Vaccinia virus, HeLa cells manifest typical morphological characters of apoptosis, and the electrophoretogram of their chromosomal DNA shows the ladder pattern. In situ apoptosis detection reveals that the location of the DNA cleavage is near the nuclear membrane, where chromatin condensation also occurs.
- Apoptosis Vaccinia virus HeLa cell

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通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142

Studies on apoptosis of HeLa cell induced by vaccinia virus

1. College of Life Sciences,Peking University

Abstract: After infecting with Vaccinia virus, HeLa cells manifest typical morphological characters of apoptosis, and the electrophoretogram of their chromosomal DNA shows the ladder pattern. In situ apoptosis detection reveals that the location of the DNA cleavage is near the nuclear membrane, where chromatin condensation also occurs.