EFFICACY OF HUMAN LEUKOCYTESINTERFERON IN CHRONIC HEPATITIS B

WU Zhen-Ou; GUAN Mei-Ying; LIN Sheng-Qing; WU Zhang-Qi

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April 1987

WU Zhen-Ou, GUAN Mei-Ying, LIN Sheng-Qing and WU Zhang-Qi. EFFICACY OF HUMAN LEUKOCYTESINTERFERON IN CHRONIC HEPATITIS B[J]. Virologica Sinica, 1987, 2(2).

Citation: WU Zhen-Ou, GUAN Mei-Ying, LIN Sheng-Qing, WU Zhang-Qi. EFFICACY OF HUMAN LEUKOCYTESINTERFERON IN CHRONIC HEPATITIS B .VIROLOGICA SINICA, 1987, 2(2) : 45.

人白细胞α-干扰素治疗乙型肝炎的疗效观察

1.
湖北医学院附属第一医院
2.
中国科学院武汉病毒研究所武汉

摘要

本文报告1983～1985年的73例乙型肝炎,是根据1984年全国病毒性肝炎会议防治标准;按临床表现、活体肝组织病理检查、血清标志物包括DNA-P以及免疫学等多项指标进行诊断与分型。并将其随机分为二组对比;一组35例应用人白细胞干扰素(IFN-α)治疗,一组38例应用聚肌胞(Poly I:C)治疗。经过3—6月的临床效果观察和免疫功能的检测表明,IFN-α组的总有效率为88.6％31/35例;其中有8例阴转,而Poly I:C组的总有效率为65.8％,未见一例阴转,两组的差异有显著性(P<0.05);并略述其机理。

EFFICACY OF HUMAN LEUKOCYTESINTERFERON IN CHRONIC HEPATITIS B

1.
Department of Infectious Diseases
2.
The First Affiltated Hospital

Abstract

Seventy-three cases with chronic hepatitis B were randamly divided into two groups,among which 35 cases were treated with interferon of human leukocytes,and 38 cases were treated with poly I:C.With several cases as the control group,the study group received interferon of human leukocytes 40000μ3/week I. M.for 3 months;and the control group was treated with poly I:C 2ml 3/week I.M.for 3 monthsThe side effect in the study group was of same manifestation:two cases with slight fever.The results showed that the ...

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通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142

EFFICACY OF HUMAN LEUKOCYTESINTERFERON IN CHRONIC HEPATITIS B

1. Department of Infectious Diseases
2. The First Affiltated Hospital

Abstract: Seventy-three cases with chronic hepatitis B were randamly divided into two groups,among which 35 cases were treated with interferon of human leukocytes,and 38 cases were treated with poly I:C.With several cases as the control group,the study group received interferon of human leukocytes 40000μ3/week I. M.for 3 months;and the control group was treated with poly I:C 2ml 3/week I.M.for 3 monthsThe side effect in the study group was of same manifestation:two cases with slight fever.The results showed that the ...