The Influence of Plasmid N3 on λ Phage Deveiopment Pathway

XU Hua; BO Qiang; DIAO Xu-Mei; ZHANG Yong-Di

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April 1989

XU Hua, BO Qiang, DIAO Xu-Mei and ZHANG Yong-Di. The Influence of Plasmid N3 on λ Phage Deveiopment Pathway[J]. Virologica Sinica, 1989, 4(2).

Citation: XU Hua, BO Qiang, DIAO Xu-Mei, ZHANG Yong-Di. The Influence of Plasmid N3 on λ Phage Deveiopment Pathway .VIROLOGICA SINICA, 1989, 4(2) : 182.

N3质粒对λ噬菌体发育途径的影响

1.
中国科学院成都生物研究所
2.
中国科学院成都生物研究所成都

摘要

诱导试验表明N_3质粒抑制λ溶源菌诱导处理时的裂解性发育途径,使λ噬菌体产率大大降低,仅为对照的10~(-5)—10~(-6)。感染实验表明N_3质粒主要抑制λ噬菌体的溶源性发育途径,其溶源菌形成率仅为对照的1.3—1.9％。从N_3质粒对λ噬菌体感染时与λ溶源菌诱导时的发育途径的不同作用的事实推测N_3质粒的某种产物(蛋白质)与λ噬菌体cI蛋白相作用,以障碍cI蛋白正常解离或聚合的方式而干扰其发育途径。
- λ噬菌体
- , N3质粒
- , 流产发育

The Influence of Plasmid N3 on λ Phage Deveiopment Pathway

1.
Institute of Biology
2.
Academia Sinica

Abstract

Plasmid N_3 inhibits inductive development in λ lysogen. It makes λ yield lower 10~(-5)—10~(-6) times than that of the contiol. Plasmid N_3 inhibits λ lysogenic development pathway on λ infection. Tire inhibition mechanism of λ development by plasmid N_3 is supposed that the polymerization and depolymerization of λ cI proteins is blocked by the interaction between λ cI protein and plasmid N_3 (probably, plasmid N_3 protein(S)).
- plasmid N3
- , λ phage
- , abortive development

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通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142

The Influence of Plasmid N3 on λ Phage Deveiopment Pathway

1. Institute of Biology
2. Academia Sinica

Abstract: Plasmid N_3 inhibits inductive development in λ lysogen. It makes λ yield lower 10~(-5)—10~(-6) times than that of the contiol. Plasmid N_3 inhibits λ lysogenic development pathway on λ infection. Tire inhibition mechanism of λ development by plasmid N_3 is supposed that the polymerization and depolymerization of λ cI proteins is blocked by the interaction between λ cI protein and plasmid N_3 (probably, plasmid N_3 protein(S)).