Effect of Human Semen and Anaerobic Bacteria Culture Fluid on Induction of Cervical Carcinoma in mice

SUN Yu; LIU Chao-Qi; LU De-Yin; ZENG Yi

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February 1992

SUN Yu, LIU Chao-Qi, LU De-Yin and ZENG Yi. Effect of Human Semen and Anaerobic Bacteria Culture Fluid on Induction of Cervical Carcinoma in mice[J]. Virologica Sinica, 1992, 7(1).

Citation: SUN Yu, LIU Chao-Qi, LU De-Yin, ZENG Yi. Effect of Human Semen and Anaerobic Bacteria Culture Fluid on Induction of Cervical Carcinoma in mice .VIROLOGICA SINICA, 1992, 7(1) : 11.

人精浆、厌氧菌培养液在HSV-2诱导宫颈癌中的作用

1.
湖北医学院病毒研究所
2.
宜昌医专微生物室
3.
中国预防医学科学院病毒所武汉

摘要

本实验应用HSV-Z诱导小鼠宫颈癌的动物模型,发现人精浆或厌氧菌培养液只引起宫颈上皮轻度增生,二者混合(SB)不仅可致宫颈癌(11.5％),而且使HSV-2诱癌率从23.1％提高到50％,同时发现SB具有抑制机体细胞免疫功能的作用,抑制ConA刺激的淋巴细胞转化及NK细胞的活性。上述结果提示SB具有促癌作用,因而也讨论了SB促癌的可能机制。
- 人精液
- , 厌氧杆菌培养液
- , 细胞免疫
- , 宫颈癌

Effect of Human Semen and Anaerobic Bacteria Culture Fluid on Induction of Cervical Carcinoma in mice

1.
Virus Research Institute
2.
Hubei Medical College
3.
Wuhan

Abstract

Co-carcinogensis of seminal plasma(S), culture fluid of anaerobic bacteria(B) and Herpes Simplex Virus type 2(HSV-2) induced cervical carcinoma inmice were studied. The results showed that there were slight displasia insingle seminal Plasma(S) group or culture fluid of anaerobic bacteria group,cervical carcinoma could be induced by SB with an induction rate of 11.5%;23.1% of the carcinoma rate in HSV-2 group and 50.0% of the rate in HSV-2+SB group. The experimental results indicated that SB was both carcino...
- Seminal plasma
- , Anaerobic Bacteria
- , Cellular Immune
- , Cervical Carcinoma

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通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142

Effect of Human Semen and Anaerobic Bacteria Culture Fluid on Induction of Cervical Carcinoma in mice

1. Virus Research Institute
2. Hubei Medical College
3. Wuhan

Abstract: Co-carcinogensis of seminal plasma(S), culture fluid of anaerobic bacteria(B) and Herpes Simplex Virus type 2(HSV-2) induced cervical carcinoma inmice were studied. The results showed that there were slight displasia insingle seminal Plasma(S) group or culture fluid of anaerobic bacteria group,cervical carcinoma could be induced by SB with an induction rate of 11.5%;23.1% of the carcinoma rate in HSV-2 group and 50.0% of the rate in HSV-2+SB group. The experimental results indicated that SB was both carcino...