Observation on the Persistance of Immunity in Humans Vaccinated with Hepatitis B Vaccine

ZHAO Wen-Bin; ZHOU Ke-Jie; WU Tao-Lin

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June 1992

ZHAO Wen-Bin, ZHOU Ke-Jie and WU Tao-Lin. Observation on the Persistance of Immunity in Humans Vaccinated with Hepatitis B Vaccine[J]. Virologica Sinica, 1992, 7(3).

Citation: ZHAO Wen-Bin, ZHOU Ke-Jie, WU Tao-Lin. Observation on the Persistance of Immunity in Humans Vaccinated with Hepatitis B Vaccine .VIROLOGICA SINICA, 1992, 7(3) : 272.

乙肝疫苗免疫持久性观察

1.
连云港市卫生防疫站
2.
连云港市卫生防疫站连云港
3.
连云港

摘要

本文比较10μg三个批号国产HB-Vac的4年免疫持久性,发现在同一年龄组免疫持久性在性别上无差异(P>0.05),但在临界保护率(S/N≥2.1)和有效保护率(S/N≥10)幼儿组明显高于成年组(P<0.05)。鉴于幼儿初免4年后有效保护率下降到60％以下,建议HBVac加强免疫可在初免3—4年进行。
- 乙肝血源性疫苗（HB-Vac）
- , 免疫持久性
- , 乙型肝炎表面抗体（Anti-HBs）

Observation on the Persistance of Immunity in Humans Vaccinated with Hepatitis B Vaccine

1.
Lianyungang Health and Anti-epidemic Station
2.
Lianyungang 222003

Abstract

The immune persistance of three batches of domestic Hepatitis B Vaccine at a dose of 10μg were studied for four years. The results showed that in the same age group there was no difference in immune persistance by sex. The critical protective rate and effective protective rate were higher in the infant groups than in the adult groups. The difference has statistical significance (P<0.05). The protective efficacy of primary vaccination in the infants group dropped to lower than 60 per cent after four years...
- Hepatitis B vaccine Immune persistance Anti-HBs

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通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142

Observation on the Persistance of Immunity in Humans Vaccinated with Hepatitis B Vaccine

1. Lianyungang Health and Anti-epidemic Station
2. Lianyungang 222003

Abstract: The immune persistance of three batches of domestic Hepatitis B Vaccine at a dose of 10μg were studied for four years. The results showed that in the same age group there was no difference in immune persistance by sex. The critical protective rate and effective protective rate were higher in the infant groups than in the adult groups. The difference has statistical significance (P<0.05). The protective efficacy of primary vaccination in the infants group dropped to lower than 60 per cent after four years...